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Kapsul Jamur Nambah VO₂max 14,8 %—Nanging Ana Sing Gedhe

Dr. Gymbro · · 4 min read
#supplements #sports nutrition #endurance #vo2max #mushroom extract #beta glucan #hypoxia

Kapsul Jamur Nambah VO₂max 14,8 %—Nanging Ana Sing Gedhe

Ringkesan: Kapsul jamur, 40 dina, lan kenaikan VO₂max nganti 14,8 % krasa kaya janji sing kebak lèngkap. Ing artikel anyar ing Antioxidants, 50 atlet enom sing ngombe 320 mg ekstrak jamur multi‑beta‑glukan saben dina ngasilake VO₂max mundhak saka 46,26 dadi 53,12 mL/kg/menit. Nanging ora ana grup placebo, ora ana randomisasi lan blinding, lan para atlet tetep nindakake latihan sakwise. Eksperimen sel ing sel jantung tikus menehi petunjuk babagan hipoksia, nanging sing dites mung senyawa tunggal, ora kapsul lengkap. Ing ngisor iki ringkesan temuan, apa sing ora bisa diparingi kawruh, lan sapa sing kudu mikir kaping pindho sadurunge nyoba.

Angka Sing Nggugah

Artikel (Kumar, Gill, Verma lan Singh, Antioxidants 2026; 15(11):1386) nglaporake menawa 50 atlet pria sehat umur 18‑22 taun ngonsumsi 320 mg sapo dina ekstrak jamur multi‑beta‑glukan sajrone 40 dina. VO₂max relatifé mundhak saka 46,26 dadi 53,12 mL/kg/menit, kenaikan 14,8 % (p < 0,001). VO₂max absolut mundhak 11,6 %. Liputan ing NutraIngredients uga nyebutake wektu nganti lelah sing nambah.

Produk iki dijual minangka kapsul "7‑in‑1 Mushroom Complex Extract". Sumber sing dakkatut ora nyantumake spesies jamur apa wae, mula aku ora bakal nebak.

Sing Gedhe: Ora Ana Placebo, Ora Ana Kontrol

Iki studi pilot tanpa kontrol, siji‑lengan, pre‑post. Ora ana grup placebo, ora ana randomisasi, lan ora ana blinding. Penulis malah nyebut asil iki minangka hypothesis‑generating.

Apa iki penting? Ana telung alesane:

  1. Latihan tetep mlaku. Para atlet nerusake program latihan rutin sajrone 40 dina. Atlet enom sing latihan 6 minggu bisa nambah VO₂max tanpa suplemen apa wae, mula desain iki ora bisa misahake pengaruh suplemen saka pengaruh latihan.
  2. Efek ekspektasi. Kabeh peserta ngerti yen padha nampa suplemen. Motivasi nduwèni peran gedhe ing tes latihan maksimal, lan ora ana apa‑apa sing ngontrol faktor iki.
  3. Populasi sempit. Kabeh partisipan pria enom sehat, dadi asil ora bisa digeneralisasi kanggo wanita, uwong tuwa, utawa wong non‑atlet.

Desainé memang ana struktur: peserta nglakoni wash‑out suplemen 14‑17 dina dhisik lan diparingi diet isokalori sing standar. Langkah iki mbantu, nanging ora bisa nggentèkaké grup kontrol.

Owah‑Owah Liyané ing Getih Lan Napas

Temuan sekunder campur‑aduk lan angel diwaca:

  • Peak Respiratory Quotient (RQ) mundhak saka 1,096 dadi 1,308. Nilai iki dhuwur banget, mula kudu ati‑ati nalika maca metrik iki.
  • Hematokrit mudhun saka 44,5 % dadi 42,1 %, kebalikan saka narasi "luwih sel abang, luweh oksigen".
  • Mean Corpuscular Volume (MCV) nambah.
  • Jumlah leukosit mudhun saka 7,53 dadi 6,80 ×10⁹/L, karo neutrophil turun lan limfosit mundhak.

Hematokrit sing luwih rendah bebarengan karo VO₂max sing luwih dhuwur iku kombinasi sing menarik, nanging studi iki ora bisa nerangake sababé. Bisa dadi efek fisiologis nyata, pergeseran volume plasma, utawa mung kebisingan data. Tanpa grup kontrol, ora ana sing bisa mastèkaké.

Eksperimen Sel: Menarik, Nanging Pitakoné Beda

Artikel iki uga nyakup bagean laboratorium. Peneliti nggunakake sel H9c2 rat cardiomyoblasts (sel jantung) lan ngetrapake hipoksia kimiawi nganggo cobalt chloride (CoCl₂). Wong‑wong mau ngetes telung senyawa kanthi kapisah:

  • Beta‑glukan 20 µg/mL
  • Taurin 40 µM
  • L‑arginine 55 µM

Kabeh telu nambah aktivitas metabolik dadi 83,65‑97,40 % dibandhingake 67,29 % ing sel hipoksia waé. Kabeh uga nurunaké ekspresi Hif1a, indikator respon hipoksia seluler. Pengukuran fungsi mitokondria nganggo Seahorse nuduhaké owah‑owahan sing ora signifikan sacara statistik.

Ana jurang gedhe antarane kerja sel iki lan uji klinis manungsa. Sel nguji senyawa tunggal ing model hipoksia kimia, déné uji manungsa mriksa ekstrak jamur lengkap ing atlet. Data sel bisa ngandhani mekanisme sing masuk akal, nanging ora bukti manawa kapsul iku kerja liwat mekanisme sing padha ing awak manungsa.

Apa Bukti Bisa lan Ora Bisa Didhukung

Bisa ndhukung: sinyal sing pantas diteliti luwih lanjut. Perubahan pre‑post sing gedhe kanthi p‑value cilik ing 50 subjek lan data sel sing nuduhaké jalur hipoksia maringi alesan kanggo nindakake trial sing bener.

Ora bisa ndhukung: klaim yen ekstrak jamur ningkataké VO₂max nganti ±15 %. Adaptasi latihan, efek ekspektasi, familiaritas tes, lan variasi pangukuran saben‑saben bisa njelasaké sebagian utawa kabeh kenaikan. Trial acak, double‑blind, lan placebo‑controlled mesthine bakal nuduhaké efek sing luwih cilik, yen ana.

Takeaway Praktis

  • Dosis sing diteliti: 320 mg/dina ekstrak jamur multi‑beta‑glukan.
  • Durasi: 40 dina. Bahan sing dakkatut ora nemtokake wektu panggunaan optimal, mula ora ana saran wektu adhedhasar bukti.
  • Sapa sing bisa kasengsem: pria enom sehat lan terlatih sing kepengin nyoba eksperimen pribadi kanthi teliti. Sanajan mangkono, anggep iki minangka eksperimen, dudu suplemen performa sing wis kabukten. Cathet asil kanthi kondisi sing konsisten.
  • Sapa sing kudu ngindhari utawa takon dhokter dhisik: wong sing alergi jamur, ibu hamil utawa nyusui, wong kanthi penyakit kronis, lan sapa wae sing ngonsumsi obat resep, utamané imunomodulator. Atlet sing wis dites uga kudu mriksa label produk lan sertifikasi pihak katelu. Iki saran umum, dudu asil saka artikel.
  • Apa sing ora kudu ditindakake: ora ngorbanaké pondasi performa sing wis kabukten (latihan terstruktur, turu cukup, nutrisi) mung kanggo ngombe kapsul.

Kesimpulan

Kenaikan VO₂max 14,8 % iku angka sing cepet nyebar, lan ora ana grup placebo dadi alesan supaya kita alon‑alon. Pilot iki maringi hipotesis kanggo peneliti, dudu asil final kanggo atlet. Tes sing bener kudu acak, placebo‑controlled, nganggo komposisi jamur sing jelas, populasi sing luwih wiyar, lan blinding. Nganti ana, jawaban marang pitakon "apa kapsul jamur tenan nambah VO₂max 15 %?" isih "durung ngerti".

Original study

Read the original research on doi.org →

This article summarizes published research for general information. It is not medical advice.

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Dr. Gymbro

Dr. Gymbro writes for Dr. Gymbro: science-backed fitness, nutrition & performance.

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