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Science & Research

Creatine da Asarar Gashi: Bayani Kan Ƙaruwa na 56 % a DHT a Binciken 2009

Dr. Gymbro · · 5 min read

Abin Da Yake Kawo Tsoro

Idan kun taɓa rubuta "shin creatine na haifar da asarar gashi?" a mashigar bincike, tabbas kun taɓa karanta wani rahoto. A shekara ta 2009, masana a wani cibiyar rugby ta Afirka Ta Kudu sun ba da rahoton cewa dihydrotestosterone (DHT) ya ƙaru 56 % bayan mako guda na shan gram 25 na creatine a rana. Idan aka rage adadin zuwa gram 5 a rana, DHT ya tsaya a kimanin 40 % fiye da matakin da ya fara. Amma matakin testosterone bai canza ba.

DHT shine androgen mafi ƙarfi da aka samu daga testosterone, kuma shi ne hormone da aka fi alaƙa da asarar gashi a maza masu al’ada. Don haka duk wata ƙaruwa a DHT na iya sa mutane su firgita. Amma ainihin abin da binciken ya nuna ya fi ƙanƙanta fiye da yadda intanet ke labarta, kuma bambancin tsakanin su yana da matuƙar muhimmanci.

Abin Da Masana Suka Gano

Wannan takarda, da van der Merwe da abokan aikinsa suka wallafa a Clinical Journal of Sport Medicine, tana bayani kan gwajin double‑blind, placebo‑controlled crossover. An gudanar da shi a kan ‘yan wasa rugby ashirin masu shekaru na koleji a lokacin kakar wasanni. Kowane ɗaya ya halarta a cikin shirin biyu, an ba su hutu na mako 6 tsakanin su.

Tsarin shan creatine da aka bi shi ne na al'ada:

  • Loading: gram 25 na creatine + gram 25 na glucose a rana na kwanaki 7
  • Maintenance: gram 5 na creatine + gram 25 na glucose a rana na kwanaki 14
  • Placebo: gram 50 na glucose a rana, sannan gram 30 na glucose a rana

An auna serum testosterone da DHT a matakin farko, a rana ta 7 da kuma a rana ta 21, tare da auna ƙwayar jiki.

Sakamakon ya nuna babu wani canji a testosterone. DHT kuwa ya ƙaru da 56 % bayan loading, sannan ya ci gaba da kasancewa 40 % fiye da matakin farko bayan makonni biyu na maintenance (P < 0.001). Dangantakar DHT : testosterone ta hau 36 % bayan loading kuma ta riƙe ƙaruwa 22 % bayan maintenance (P < 0.01). Marubutan sun ba da shawarar cewa creatine na iya ƙara juye‑juye testosterone zuwa DHT, kuma sun kira a yi ƙarin bincike kan amincin dogon lokaci.

Abubuwan Da Binciken Bai Nuna Ba

A nan ne abubuwan da ke ɓacewa a tattaunawar yanar gizo: ba a auna asarar gashi ba. Binciken ya bi diddigin hormone da ƙwayar jiki, ba yawan gashi, ragowar gashi, ko wani sakamakon dermatology ba. Tsallakewa daga "DHT ya ƙaru" zuwa "za ka rasa gashinka" ba hujja ba ne, tsinkaya ne kawai.

Iyakokin Binciken

  • Karamin rukunin mutane. ‘Yan wasa ashirin ne kawai, masu shekaru 18‑23.
  • Kadan lokaci. Makonni uku ba su ba da haske kan abin da ke faruwa bayan watanni ko shekaru.
  • Rukuni na musamman. ‘Yan wasan rugby ne, wadda ke nufin suna da motsa jiki mai tsanani da canjin hormone da ke faruwa a lokaci guda.
  • DHT a serum kawai. Matakin DHT a jinin ba lallai ya nuna yawan DHT a fatar kai ba, inda enzymes da ƙwayoyin gashi ke da muhimmanci.

Haka kuma, wasu gwaje‑gwaje da suka duba creatine da androgen ba su ga hauhawar DHT ko alaƙa mai ma’ana ba. Wannan bincike guda ɗaya ne da ya yi fice, amma ba zai iya zama hujja ta ƙarshe ba.

Me Ya Sa DHT Ke Da Muhimmanci Ga Gashi?

Asarar gashi a maza na buƙatar abubuwa biyu: androgen masu yawo a jini da gadon ƙwayoyin gashi da ke da ƙwazo ga DHT. Maza da ba su da wannan gado na iya kasancewa da DHT mai yawa amma ba su rasa gashinsu ba. Maza da ke da gado na iya rasa gashi ko da matakin hormone ɗin su na matsakaici ne.

Saboda haka magunguna kamar finasteride, wadanda ke toshe enzyme da ke juya testosterone zuwa DHT, suna taimakawa ga yawancin mutane. Ƙaruwa a serum DHT, ko da a zahiri, ba lallai ta haifar da raguwar gashi ga kowa ba. Tsoron da ya fi tasiri shi ne ga mutanen da ke da tarihin asarar gashi a iyali – su ne za su iya lura da canjin idan DHT ya tashi sosai. Wannan tsinkaya ne, ba a tabbatar da shi ba dangane da creatine.

Loading vs. Maintenance – Menene Ma’anarsa?

Binciken ya yi amfani da dabara loading ta al'ada: gram 20‑25 a rana na mako ɗaya don cika ajiyar creatine a tsokoki da sauri, sannan gram 3‑5 a rana a matakin maintenance. Canjin DHT mafi girma ya faru a lokacin loading, kodayake ƙaruwa ta ci gaba a kan ƙarami a matakin maintenance.

Loading ba wajibi ba ne don creatine ya yi aiki. Shan gram 3‑5 a rana ba tare da loading ba yana kai matakin creatine a tsokoki a kusan makonni 3‑4. Babban bambanci shi ne saurin samun fa’ida.

Waɗanda Ya Kamata Su Kula Da Wannan

Mafi yawan masu ɗaukar creatine ba su da dalilin firgita. Amma wasu rukuni na iya buƙatar tunani mai zurfi:

  • Maza da ke da tarihin iyali na asarar gashi sosai, musamman waɗanda ke lura da ragowar launin gashi a farkon shekaru.
  • Masu amfani da magungunan toshe DHT (kamar finasteride) da ke shirin tattaunawa da likita game da ƙara creatine.
  • Mutane masu kulawa da lafiyar jiki sosai kuma ba sa son ƙara wani abu da ba a san sakamakonsa na dogon lokaci ba.

Idan kuna cikin wani daga cikin waɗannan rukuni, za ku iya yin ɗaya daga cikin zaɓuɓɓuka: daina loading, ragewa zuwa gram 3 a rana, ko kuma auna yawan gashi da ragowarsa lokaci‑lokaci. Idan kun ga canji, za ku iya dakatar da shan creatine kuma ku sake duba. Amfanin creatine ga ƙarfi, ƙarin lean mass, da ingancin horo ya kasance cikin mafi karɓa a ilimin abincin wasanni, don haka kimanta su da haɗarin da ba a tabbatar ba wani yanke shawara ne na kanku.

Takaitaccen Bayani

Binciken rugby na 2009 ya nuna cewa creatine na ƙara DHT sosai yayin da testosterone ya tsaya. Amma wannan gwaji karami ne, ba a duba gashi ba, kuma ba a tabbatar da tasirin wannan ƙaruwa a kan dogon lokaci. Don haka, a matsayinmu na masu karatu, za mu iya cewa creatine na iya zama hanya da za a bi amma ba a tabbata da tasirin asarar gashi ba. Ga mutane da yawa, wannan ba ya wuce fa’idodin creatine da aka tabbatar da su; ama maza masu tarihin asarar gashi na iya duba kariya ta hanyar rage loading ko auna yanayin DHT a kai‑a‑kai.

Original study

Read the original research on pubmed.ncbi.nlm.nih.gov →

This article summarizes published research for general information. It is not medical advice.

DG

Written by

Dr. Gymbro

Dr. Gymbro writes for Dr. Gymbro: science-backed fitness, nutrition & performance.

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