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Nutrition

AstraGin:提升乳清蛋白吸收的隐藏标签成分

Dr. Gymbro · · 1 min read

AstraGin:提升乳清蛋白吸收的隐藏标签成分

摘录:在你的预锻或蛋白粉标签上,可能藏着一种你忽视的微量成分——AstraGin。最新的人体先导试验显示,它能让60‑80岁成人的亮氨酸吸收提升约14%,离氨酸提升约8%,全部必需氨基酸的吸收增加近13%。血清中的zonulin(肠道通透性指标)也下降了13%。然而,力量和肌肉质量的差异并未达到统计学显著,且研究仅招募了30名受试者。下面我们来看看这些数据到底说明了什么。


你大概已经扫过标签底部那行极小的字——AstraGin。听起来更像奇幻小说里的名字,而非补剂成分。最新的人体先导试验暗示,这个鲜为人知的成分或许能帮助身体更高效地利用乳清蛋白,尤其是在60岁以上的人群中效果最为显著。冲动购买前,先来看看这项研究的发现和局限。

AstraGin 是什么?为什么它频繁出现在补剂里?

AstraGin 是 NuLiv Science 推出的品牌配方,融合了黄芪(Astragalus membranaceus)和三七(Panax notoginseng)的提取物。其活性成分为皂苷——一种被认为能影响营养物质跨肠道黏膜的植物化合物。对补剂厂商来说,卖点很简单:加入少量,就能提升其他成分的吸收。这也是它常见于预锻、蛋白粉以及多成分配方中的原因。

研究人员把这两种皂苷统称为 APS(Astragalus & Panax saponins)。此前,APS 是否真的能在人类身上提升乳清蛋白利用率尚不明确,这也是本次试验值得关注的原因。

研究设计是怎样的?

这项工作于2026年发表在《Nutrients》上,作者是一支来自台湾的团队(庄、严、林、沈),采用随机、双盲、安慰剂对照、交叉设计。30位健康成年志愿者被平均分入三个年龄段:18‑25、26‑59、60‑80岁,每组10人。

研究分为两个阶段:

  • 单剂量阶段:受试者在同一天分别摄入含 APS 或安慰剂的乳清,监测血液中氨基酸出现的速度和峰值。
  • 四周阶段:每日补充 APS 的同时进行轻度阻力训练(椅子深蹲、墙壁俯卧撑、髋桥,各三组),并每日摄入 0.8 g/kg 乳清蛋白。期间测定氨基酸动力学、肌肉功能以及肠道健康指标。

依据 Ergo‑Log 报道,剂量为每日两次、每次 50 mg AstraGin,即每日总量 100 mg。

引人注目的数据

单剂量实验中,血药浓度曲线下面积(AUC,衡量总体氨基酸暴露)相较安慰剂提升:亮氨酸 +6.67%,离氨酸 +3.62%,而异亮氨酸仅 +0.15%,几乎没有意义。

四周结果更为醒目:

  • 亮氨酸吸收:+14.07%
  • 离氨酸吸收:+8.34%
  • 异亮氨酸吸收:+6.33%
  • 60‑80岁组的必需氨基酸总吸收:+12.74%
  • 血清 zonulin:APS 组下降 13.01%,而安慰剂组仅 -0.9%

Zonulin 是常用的肠道通透性标志物,下降意味着肠屏障更紧密。这为吸收提升提供了一个有趣的机制解释,尽管 zonulin 本身作为生物标志物仍有争议,且本研究无法证明屏障变化直接导致氨基酸增加。

老年人群的信号尤为重要,因为年龄增长会削弱肌肉对膳食蛋白的合成反应,这种现象被称为“合成抵抗”。任何能让更多亮氨酸等必需氨基酸进入循环的手段,都会受到关注。

哪些结果未达显著性?

这里必须把标题的热度降温。握力在 APS 组提升了 5.20%,安慰剂组为 2.44%;肌肉质量增长 0.85% 对比 0.68%。作者把这些描述为肌肉功能的提升,但正如 Ergo‑Log 所指出的,力量和肌肉质量的差异并未达到统计学显著。同样,只有部分氨基酸的变化达到了显著水平。

通俗来说:吸收的数据看起来有前景,但并没有坚实证据表明 AstraGin 能让你长出更多肌肉或提升力量。0.17% 的肌肉质量差距在如此小的样本里完全可能是噪声。

安全性方面,四周内肝、肾功能指标均未出现不良变化。

剂量:每日 100 mg 与 EFSA 建议的 35 mg 对比

值得注意的是,研究使用的 100 mg/天剂量几乎是欧洲食品安全局(EFSA)在2020年评估中给出的安全上限 35 mg/天的三倍。四周内未出现肝肾问题固然让人放心,但这并不等同于长期安全性数据。如果你在寻找 AstraGin 的推荐剂量,要注意市面上多数产品的实际含量远低于本试验用量,真实使用效果可能与实验条件不匹配。

AstraGin 真有用吗?诚实的结论

这是一项仅30人、四周、轻度阻力训练的“小试点”。此类聚焦单一成分的试验往往使用商业价值较高的品牌配方,独立复现显得尤为关键。吸收提升的发现值得关注,但仍不能算作决定性结论。

实用建议

  • 最可能受益的人群:老年训练者以及怀疑自己蛋白吸收或消化不良的人,因为最大效应出现在 60‑80 岁组。
  • 使用方式:试验中是与乳清蛋白一起服用的,所以搭配蛋白粉是最合逻辑的做法。
  • 别盲目砸钱:如果你的蛋白摄入和训练已经到位,5‑14% 的特定氨基酸提升对整体表现的改变可能并不明显。
  • 先打好基础:总蛋白摄入、餐次分配、渐进负荷和充足睡眠仍然远远压倒任何吸收助剂的作用。
  • 仔细查看标签:很多产品把 AstraGin 放在专有混合物里,实际剂量往往难以得知。

AstraGin 可能是一个帮助你更好利用蛋白质的聪明小帮手,尤其是随着年龄增长时。但在更大规模、时间更长、独立完成的研究证实它能真正提升肌肉和力量之前,建议把它视作“有潜力的选择”,而非必备品。

Original study

Read the original research on pubmed.ncbi.nlm.nih.gov →

This article summarizes published research for general information. It is not medical advice.

DG

Written by

Dr. Gymbro

Dr. Gymbro writes for Dr. Gymbro: science-backed fitness, nutrition & performance.

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