Ketone Drinks in the Heat: Longer Endurance and Sharper Memory?
Ketone drinks are supposed to be for fat-burning biohackers, but a new heat-stress trial suggests they might also help you finish stronger. In 17 trained men, ketone monoester plus caffeine extended time to exhaustion to 8.9 minutes versus 7.0 with carbs plus caffeine, after 90 minutes of loaded treadmill work at 34 °C. Working-memory accuracy on the 1-back task improved too, while heart rate and core temperature didn't differ meaningfully. But 2-back, reaction time and the hit-and-avoid task showed no benefit, and the study was small, male-only and single-session. Here's what the data show, and what they don't.
One 0.35 g/kg Creatine Dose Fought Sleep-Loss Brain Fog in Hours
Creatine is the most trusted supplement in the gym, but a 2024 study suggests it may also fight sleep-deprivation brain fog within hours. In the study, a single 0.35 g/kg dose, roughly 25-28 g for most adults, changed brain energy markers, prevented a drop in brain pH and improved cognitive performance and processing speed during 21 hours without sleep. That's about five times a normal 3-5 g daily dose, and the study was small and lab-based. GI upset is a real possibility, and nobody tested repeated mega-dosing. Here's what the research really shows, and why you shouldn't change your daily routine yet.