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Science & Research

Pembakaran Lemak Kafein: Ngapa Dosis 3 mg/kg Luwih Apik Tinimbang Mega‑Dosis 9 mg/kg

Dr. Gymbro · · 3 min read

Kowe mbok kira nambah dosis kafein bakal nggandakake pembakaran lemak?

Penelitian acak anyar nuduhaké kosok balèn: dosis paling gedhé malah paling ora duwe pangaruh marang oksidasi lemak, lan dosis paling cilik sing efektif uga sing paling ora ngganggu jantung.

Ringkesan Studi (30 Detik)

Peneliti dipimpin Gong lan dipun‑terbitaké ing Journal of the International Society of Sports Nutrition nyoba efek kafein marang klompok cilik mahasiswa wanita sing over‑weight/obesitas lan ora aktif. Sèwelas partisipan (rata‑rata umur 20,2 taun, BMI 26,36 kg/m²) nindakake papat sesi: plasebo (selulosa) utawa kafein 3 mg, 5 mg, utawa 9 mg per kilogram bobot awak (PubMed 42120324).

Saben sesi diwiwiti kanthi 60 menit istirahat lungguh, terus dilanjutake 40 menit mlaku ing treadmill ing zona FATmax – intensitas ngendi awak ngobong lemak paling akèh. Kalorimetri indirek dipigunakaké kanggo ngrekam panggunaan bahan bakar. Tekanan darah, denyut jantung, lan indeks perfusi driji (PI) uga dicathet kanggo ngawasi respon kardiovaskular.

Temuan Pokok: Luwih Akeh Dosis, Ora Kasil

  • Dosis 3 mg/kg lan 5 mg/kg nambah oksidasi lemak dibanding plasebo lan dosis 9 mg/kg (p < 0,05).
  • Dosis 9 mg/kg ora nambah manfaat metabolik apa‑apa.

Oksidasi karbohidrat uga mundhak, nanging polaé béda. Dosis 3 mg/kg lan 5 mg/kg ngasilaké oksidasi karbohidrat sing luwih endhek tinimbang dosis 9 mg/kg, nuduhaké yèn dosis menengah ngarahaké panggunaan energi marang lemak, déné dosis paling dhuwur ora ngowahi.

Kafein ora ngowahi denyut jantung istirahat utawa oksidasi substrat nalika ora olahraga. Pengaruh bakar lemak mung muncul nalika olah raga, dudu nalika lagi lungguh.

Pengaruh Kardiovaskular: Jantungmu Krasa

  • 3 mg/kg: ora ana perubahan signifikan ing denyut jantung lan tekanan darah nalika olah raga.
  • 5 mg/kg: denyut jantung lan tekanan darah nambah sacara signifikan nalika olah raga.
  • 9 mg/kg: kenaikan signifikan ing denyut jantung lan tekanan darah.
  • Kabéh dosis kafein: indeks perfusi (PI) mudun (p < 0,05). PI iku ukuran perfusi perifer ing driji.

Para panulis nyimpulake yèn dosis 3 mg/kg nyedhiyakake keseimbangan paling apik antara stimulasi oksidasi lemak lan minimalisasi beban kardiovaskular ing populasi iki. Dosis 5 mg/kg uga nambah oksidasi lemak, nanging karo beban kardiovaskular sing luwih gedhé.

Praktèk Kanggo Keseharian

Dosis

Titik manisé yaiku 3 mg/kg. Contoné, wong seberat 70 kg bakal nampa kira‑kira 210 mg kafein. Dosis 5 mg/kg kira‑kira 350 mg, lan 9 mg/kg kira‑kira 630 mg. Iki aritmetika sederhana, ora adhedhasar tabel ing makalah.

Wektu

Ing protokol, partisipan istirahat 60 menit sawisé ngonsumsi kapsul sadurungé mlaku 40 menit. Mung wektu iki sing didhukung data. Abstrak ora nyebut partisipan puasa, mula “cardio puasa” ora bisa dipastèkaké saka studi iki.

Intensitas

Olahraga dilakokaké ing zona FATmax, intensitas moderat sing diukur saka oksidasi lemak maksimum. Hasil ora kudu dianggep cocok kanggo latihan interval keras utawa sesi daya tahan dawa.

Sapa Sing Cocok

Temuan iki nganggo wanita enom sing ora aktif, over‑weight/obesitas, lan nindakake olahraga akut kanthi intensitas rendah – persis klompok sing diteliti.

Sapa Sing Kudu Waspada utawa Ngindari

Abstrak ora nggatekake wong sing duwe masalah jantung utawa hipertensi. Amarga dosis 5 mg/kg lan 9 mg/kg nambah denyut jantung lan tekanan darah, sapa wae sing nduwèni hipertensi, kelainan jantung, utawa sensitif marang kafein kudu takon dhisik marang profesional kesehatan sadurunge nyoba. Ngindhari dosis dhuwur iku pilihan wicaksana kanggo sapa waé.

Apa Sing Ora Bisa Dikatakan Studi Iki

  • Ukuran sampel cilik: mung 11 partisipan, ora cukup kanggo nyimpulake yèn asil iki umum kanggo populasi luwih gedhé.
  • Keterbatasan populasi: mung wanita enom. Pria, atlet, wong tuwa, lan wong sing rutin ngonsumsi kafein ora kalebu.
  • Studi akut: mung siji sesi, ora ngukur efek jangka panjang utawa adaptasi latihan minggu demi minggu.
  • Oksidasi lemak vs. penurunan lemak: peningkatan oksidasi lemak sajrone 40 menit mlaku ora mesti ateges lemak awak ilang luwih akèh ing wektu suwe.
  • Penurunan PI: kabeh dosis ngurangi indeks perfusi driji, nanging abstrak ora nerangake makna klinisé. Bisa dadi sinyal efek vaskular, ora bukti kerusakan.

Ringkesan

Ing trial acak cilik iki, kafein 3 mg/kg maringi peningkatan oksidasi lemak dibandhingake plasebo tanpa nambah denyut jantung lan tekanan darah sing katon ing dosis luwih dhuwur. Dosis 9 mg/kg ora nambah manfaat metabolik apa‑apa. Temuan iki ndhukung penggunaan dosis moderat adhedhasar bobot awak tinimbang dosis gedhé, nanging isih ana pitakon babagan efek jangka panjang lan populasi liya.

Source: Gong et al., Journal of the International Society of Sports Nutrition. DOI: 10.1080/15502783.2026.2670558.

Original study

Read the original research on pubmed.ncbi.nlm.nih.gov →

This article summarizes published research for general information. It is not medical advice.

DG

Written by

Dr. Gymbro

Dr. Gymbro writes for Dr. Gymbro: science-backed fitness, nutrition & performance.

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