A Mushroom Capsule Lifted VO2max 14.8%—But There's a Big Catch
A mushroom capsule, 40 days, and a 14.8% rise in VO2max sounds almost too good to be true. In this new Antioxidants paper, 50 young male athletes taking 320 mg/day of a beta-glucan-rich multi-mushroom extract improved from 46.26 to 53.12 mL/kg/min. The big catch is that there was no placebo group, no randomization and no blinding, and the athletes kept training throughout. Cell experiments on rat heart cells add a hypoxia-related hint, but they tested single compounds, not the capsule. Here's what the study found, what it can't tell us, and who should think twice.
HMB Boosted Cardio Fitness, Not Strength, in New 2026 Trial
HMB is usually sold as a way to hold onto muscle and build strength, but a new triple-blind trial found something different. In 90 men, a high personalized dose of liquid HMB free acid (90 mg per kg of fat-free mass daily) plus high-intensity functional training raised VO2max and threshold markers more than placebo. The effect was clearest in trained men, and isometric leg strength did not budge. Here is the dose math, how it compares with the standard 3 g, and who might actually benefit.
3 g Arginine + 500 mg Vitamin C: Testosterone Up 26% in Lifters
Arginine has long been written off as an overhyped nitric oxide booster, but a new randomized trial adds a twist: pair it with vitamin C. In 50 male bodybuilders, 3 g of arginine (split into three doses) plus 500 mg of vitamin C for 45 days significantly raised testosterone and VO2max versus placebo, and body fat dropped. Growth hormone, cortisol and nitrogen balance did not significantly differ between groups. It's a cheap stack worth watching, but it comes from one small trial, and higher testosterone doesn't guarantee more muscle.